The N-terminal ATP-dependent ligase domain belongs to the covalent nucleotidyltransferase enzyme superfamily that includes classic RNA/DNA ligases and mRNA capping enzymes. We’ve shown that: (i) each ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo. I suggest that ∼90% of Pol II initiation events in yeast represent transcriptional noise ...

MicroRNAs interact with proteins from the Argonaute family to degrade messenger RNA, "but because there are no Argonaute proteins in this yeast species, something else is happening and the ...

To the growing list of factors required for the export of messenger RNA from nucleus to cytoplasm can now be added Yra1. Yeast Yra1 and its metazoan orthologues bind mRNAs and interact with ...

MicroRNAs interact with proteins from the Argonaute family to degrade messenger RNA, “but because there are no Argonaute proteins in this yeast species, something else is happening and the ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public Domain) Uracil was first discovered in 1900 by the Italian chemist Alberto Ascoli ...

RNA splicing is a cellular process that is critical ... is more complicated than it is in some model organisms like yeast, even though it's a very conserved molecular process.

RNA splicing is a cellular process that is critical ... is more complicated than it is in some model organisms like yeast, even though it's a very conserved molecular process.