Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

引言在我们体内，数以亿计的细胞每天都在进行着极其复杂的生命活动，其中翻译过程扮演着至关重要的角色。翻译是基因表达的最后一步，它通过核糖体（ribosome）将mRNA上的遗传信息转化为蛋白质，驱动细胞的功能。然而，尽管翻译过程已经被广泛研究，研究人员却一直未能完全解开一个关键谜团：多个核糖体如何协同工作来高效地 ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

"Ribosomes are very large macromolecular machines that very rapidly and precisely decode mRNA into protein. For a long time, they've been viewed as kind of 'dumb code-reading machines' that don't ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

“It was intriguing to me that I could go to grad school and get paid to do that,” he says. METHODS: In biochemist David Giedroc’s lab at Texas A&M University, Cornish studied how ribosomes translate ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...