总之，phi027 bacteriophage在C. difficile的生理和毒力中扮演了关键角色。 通过去除prophage，研究人员揭示了其在孢子形成、adhesion和毒素产生中的重要作用。 这些结果为C. difficile的流行病学研究和治疗策略的开发提供了重要的科学依据。

Virulent bacteriophages were initially defined in 1959 by Adams as “a phage that lacks the ability to lysogenize”. Phages can undergo two types of replication: lytic or lysogenic replication.

Rapid design of bacteriophage cocktails to suppress the burden and virulence of gut-resident carbapenem-resistant Klebsiella pneumoniae. Journal: Cell Host & Microbe Published: 2024-11-13 ...

The lysogenic cycle, or non-virulent infection, involves the virus assimilating its genome with the host cell’s genome to achieve replication without killing the host. Bacteriophage (phage) are ...

The Ebola virus in West Africa that has killed 11,000 is not more virulent than prior strains as had been feared, according to a study published Tuesday. Researchers with the National Institutes ...

Bacteriophage can play an important role in microbial control, ... Virulent Clostridium perfringens Bacteriophage Susfortuna Is the First Isolated Bacteriophage in a New Viral Genus ### ...

The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent infection, involves a virus taking control of a host cell ...

A study publishing March 10th in PLOS Pathogens by Ananthu James and Narendra Dixit at Indian Institute of Science, India suggests that HIV-1 is more virulent when transmitted through penile ...