Figure 1: Epididymal and testicular histology in Tarbp2-/-mice. Figure 3: In situ hybridization and immunohistochemistry of GH1, Tnp2 and Prm2. For histological evaluation, we fixed dissected ...

The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT ...

In some, the RNA-binding region is adjacent to a DNA-cutting part of the protein. Others appear to bind to other proteins, which suggests they might help direct those proteins to DNA targets.