This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

In addition, Nilotinib augmented atherosclerosis in ApoE−/− mice and blocked reperfusion and angiogenesis in a hindlimb-ischemia model ... effects on vascular endothelial cells, which may ...

A 3D model accurately mimicking the blood-brain barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel ... Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular ...

Current standard of care is a combination of drugs that target vascular growth factor receptors in order to kill tumor endothelial cells (TECs) and deprive the tumor of its blood supply ... Shreeram ...