If you inherit a gene mutation for breast cancer, it means that you got it from one or both of your parents. Many mutations, such as those found in the well-known BRCA1 and BRCA2 genes ...

However, most DNA mutations do not alter a protein, they only alter it slightly so its appearance or function is not changed. There are many different types of mutations which can arise in DNA.

With base substitution mutations, only a single nucleotide within a gene sequence is changed, so only one codon is affected (Figure 1). Insertions and deletions are two other types of mutations ...

AIP (Aryl Hydrocarbon Receptor Interacting Protein) is the name of the gene which causes pituitary adenomas in some families with acromegaly and occasionally prolactinomas, and very rarely with other ...

This allows the duplicated gene to accumulate further mutations without this selection pressure. Numerous mutations over time can give rise to related genes but with a new specialised function.

Scientists compared blood from frequent, long-term donors to that of more seldom ones and saw some key genetic differences in ...

Today, leukemia patients undergo genetic analysis to identify mutations and select the most ... the researchers have identified two cell types—one "stronger" and the other more "sensitive ...

Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells.

Mutations in the BRCA1 gene that are either inherited (germline ... The men had either been tested for germline (166), somatic (280), or both types (four) of genetic variants of BRCA1, BRCA2 ...

Men who had given blood more than 100 times in their life were more likely to have blood cells carrying certain beneficial mutations, suggesting that donating blood promotes the growth of these cells ...