At this point, translation must be terminated, and the nascent protein must be released from the mRNA and ribosome. Termination of Translation There are three termination codons that are employed ...

The research field of "cellular IRESes" lay dormant for decades, as there was no uniform standard of reliable methods for the ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

The sequence of the RNA component, the aptamer, can be fused to the 3' end of the gene of interest, similar to the addition of a FLAG tag or GFP to a protein of interest. When transcribed, the final ...

Ribosomal RNA (rRNA) is a component of the ribosomes, the cellular machinery responsible for protein synthesis. rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and ...

The key structural features of tRNA include: The specificity of tRNA-amino acid interactions and the accuracy of codon-anticodon recognition ensure the faithful translation of the genetic code into ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through ...

In the Protein Engineering and Evolution ... the role of RNA modifications in cells. With RNA modifications affecting stability, promoting translation, and influencing its location within the ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.