Termination of pol II transcripts, however, is more complex. Transcription of pol II genes can continue for hundreds or even thousands of nucleotides beyond the end of a noncoding sequence.

As in prokaryotes, eukaryotic repressor molecules can sometimes bind to silencer elements in the vicinity of a gene and inhibit the binding, assembly, or activity of the transcription complex ...

a multi-protein complex known to regulate transcription elongation. By targeting the BRD4-containing CDK9 complex in cultured cells, the scientists discovered that cell responses to oxygen ...

The unexpected discovery may provide scientists with new insights into how cancer develops — and how to combat it.

We are also refining and applying ultrahigh-resolution spectroscopy techniques to dissect multistep complex biochemical processes using ... Single-Molecule Nanoscopy Elucidates RNA Polymerase II ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...