We are interested in mechanisms that regulate RNA Stress Granule (SG) and Processing Body (P-body) formation in cells. These two types of RNA granules aggregate translationally-silenced mRNAs and ...
Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...
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