Nephronophthisis (NPH) is a recessive cystic kidney disease responsible for 10% to 20% of pediatric end-stage renal disease cases. NPHP1 (nephrocystin 1) is the most frequently implicated among over ...

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study. Researchers focused on a group of interacting genes called the Hippo pathway, which serve as ...

The HIPPO pathway can modulate EMT by regulating YAP/TAZ activity. The interplay between these pathways influences EMT dynamics, impacting liver regeneration and disease progression.