这项研究中，研究人员开发了一种新型鼻腔喷雾（nasal spray），其能清除工程化改造拥有人类样阿尔兹海默病症状小鼠大脑中的tau蛋白。 在阿尔茨海 ...

Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

In healthy individuals, the protein tau stabilizes the tubular building blocks (microtubules) that make up the long projections of the nerve cells. During the development of Alzheimer's disease ...

Tau is a protein that is found in cells of the central nervous system and is involved in the assembly and stabilisation of neuronal microtubules – channels used to transport substances to ...

A team of researchers from the University of Cologne has made an important contribution to understanding the role of the tau protein in Alzheimer's disease. A specific variant of the tau protein ...