Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

Abnormal accumulation of tau protein in the brain has been associated with neurodegeneration and cognitive decline in AD patients. BIIB080 is an investigational antisense oligonucleotide therapy ...

Neurofibrillary tangles (NFTs) are neurobiological lesions that are found in brain cells of patients with Alzheimer's disease (AD). They consist of aggregates of abnormally phosphorylated tau ...

When exposed to glutamate, the organoids—particularly the ones derived from patients with neurodegenerative ...