近日,美国得克萨斯大学西南医学中心Yunsun Nam团队揭示了癌症相关突变如何通过改变METTL3-METTL14复合体对RNA甲基化(m6A)的特异性来促进肿瘤发生。研究发现,METTL14的R298P突变能够改变m6A的序列偏好,优先修饰含有GGAU ...
RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...
Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...