A new strategy for the modulation of ribozyme-mediated RNA cleavage may ... mechanisms other than regulation at the level of transcription,” he says, and ribozymes seemed a logical choice.

A group of researchers led by Professor Claudia Höbartner at the University of Würburg (JMU) has now uncovered the three-dimensional structure of a very special ribozyme: SAMURI. This is an RNA ...

When a self-cleaving ribozyme is embedded in the mRNA, the spontaneous self-cleavage of ribozyme ... When a normal stem cell erroneously transforms into a cancer cell, the biosensor would switch on a ...