How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...

1). In the 'off' state, the Lac inhibitor represses the lac operon, which prevents expression of the Tet repressor and the target gene. Additionally, a short hairpin RNA (shRNA) against the target ...

First, pAurora2 releases the blockade of translation of the target gene on the mRNA strand, and second, the system suppresses ...

Highlights from the oral presentation include: Scribe engineered novel, potent epigenetic editors (ELXRs) using newly identified repressor domains to durably and effectively silence gene ...