How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease. In the alternate pathway ...

You have full access to this article via your institution. To demonstrate the power of PCR–mediated recombination and provide an example of the general utility of the method, we constructed ...

Unlike its DNA repair role in somatic cells, homologous recombination has a distinct role in meiosis in ensuring proper chromosome segregation. In yeast, an early step of the meiotic program is the ...

Lee County Government, through its Strategic Services Department, has enacted a new policy for the recombination of property ...

While this shuffling, known as recombination, is essential for genetic diversity, errors in the process can lead to serious reproductive issues. These failures can result in genetic errors that ...

Sensitivity to ionizing radiation is compelling evidence that BRCA1-and BRCA2-deficient cells are defective in repair of DSBs. As discussed above, 2 separate pathways play major roles in DSB repair in ...