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Bacterial small RNA promotes gut colonization by regulating sialic acid metabolism, research revealsImportantly, ManS was produced by a noncanonical biogenesis mechanism: The ribonuclease RNase III, which usually cuts double-stranded RNA, cleaves at a single-stranded region in the mRNA 3'UTR.
MicroRNAs (miRNAs) are generated from local hairpin structures by the action of two RNase III-type proteins, Drosha and Dicer. Mature ∼22-nucleotide (nt) miRNAs are then bound by Ago-subfamily ...
Importantly, ManS was produced by a noncanonical biogenesis mechanism: The ribonuclease RNase III, which usually cuts double-stranded RNA, cleaves at a single-stranded region in the mRNA 3′ UTR.
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