The final word in target validation is to reintroduce an RNAi-resistant version of the target gene product into depleted cells and show recovery of function. This can be challenging for large sets ...

Alnylam Pharmaceuticals exceeded Wall Street's expectations with strong revenue growth and significant commercial progress.

The ability to trigger RNA interference in mammalian cells provides unprecedented opportunities for probing the functions of genes. Many products and resources are there to help. Laura Bonetta ...

While there are RNAi products on the marketplace, with Alnylam becoming the first company to get a product approved in 2018, it is difficult to get this class of drug distributed through the brain ...

Scientists seek innovative approaches to address this health crisis, some of which are therapeutics poised to treat CVD in new ways. RNA interference (RNAi) therapeutics silence genes, disrupting the ...

ALNY reports better-than-expected fourth-quarter results as both earnings and revenues beat estimates driven by higher ...

Her writing focuses on gene editing technology, cell and gene therapies, and the regulatory space. View Full Profile. Learn about our Editorial Policies. The natural RNAi mechanism can be directed by ...