and do not require RNA-dependent RNA polymerase (RdRP) or amplification mechanisms. Other loci form small RNAs after the primary transcripts are processed through dsRNA-forming mechanisms that ...

There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

RNA repair enzymes capable of sealing 2’,3’-cyclic-PO 4 /5’-OH breaks or 3’-OH/5’-PO 4 breaks are present in diverse taxa in all phylogenetic domains of life. ATP-dependent RNA ligases join 3’-OH and ...

Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...

Many of the most devastating infectious diseases are caused by RNA viruses, and Model Medicines is working on one compound to kill them all. The AI drug discoverer’s oral small molecule was able ...