Here the authors develop NaP-TRAP, an assay to measure translation in a frame-specific manner, revealing dynamic ... of RNA Pol II, the authors show the regulation of transcription by TBPL1 ...

The structural features of Mediator and TFIID (conformationally dynamic, extended shape ... The Mediator complex as a master regulator of transcription by RNA polymerase II. Nat Rev Mol Cell Biol 2022 ...

"In bacterial cells, transcription and translation take ... Using this, the scientists captured several minutes of the dynamic interplay between RNA polymerase and the ribosome.

Transcription, which converts DNA into RNA, and translation ... which is the unpredictable and dynamic nature of transcription. It is one of the reasons why cells in the same tissue or culture ...

We are particularly interested in biomolecular condensates, a class of membraneless cellular compartments that concentrate factors involved in nearly every step of RNA metabolism from transcription ..

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).