这在很大程度上受到了过去 60 多年关于 RNA 结构的错误观念的影响。王运星实验室的研究结果颠覆和更正了这些观念,并提出了用“准等能量”分子构象转换概念,来概括全新的 RNA 分子在溶液中的行为。
They say that change takes time. Well, that's not the case for RNA. The small biological molecule acts like a switchboard ...
Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
They say that change takes time. Well, that's not the case for RNA.The small biological molecule acts like a switchboard ...
Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved ...
No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...
UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.
In plants, secondary and tertiary RNA structures, such as G-quadruplexes, play vital roles, especially under conditions favoring structural stability, such as low temperatures. Despite the ...