Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

The findings suggest that the control of RNA splicing, a process that is fundamental to gene expression, is more complex than previously known. Splicing in more complex organisms, like humans ...

However, this approach does not address transcriptome complexity in alternative splicing and transcription ... The next big challenge for RNA-Seq is to target more complex transcriptomes to ...

They can also be within the exon.” RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence ...

The "RNA Analysis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F" report has been added to ResearchAndMarkets.com's offering.The Global RNA Analysis Market was ...

Ultimately, the spliced messenger RNA consists of only protein-encoding ... It is absolutely vital that the splicing complex accurately recognizes exon-intron-exon junctions so the needed cuts ...

A post-splicing complex deposited upstream of each exon-exon junction tags mRNAs for nuclear export ... These nuclear sequence shufflings are implicated increasingly in mechanisms such as RNA-export ...

Since inosine is interpreted as guanosine (G) by the cellular machinery, A-to-I editing can alter codons, splicing sites, and miRNA binding sites ... and structural biology approaches will provide a ...