引言与DNA不同，RNA不仅是基因表达的中介，还是细胞内多种复杂生物学过程的关键调控因子。近年来，RNA编辑作为RNA分子的一种天然修饰过程，引起了科学界广泛的兴趣。RNA编辑技术不仅能够精确调控基因表达，还为治疗各种遗传性疾病和复杂疾病提供了新的可能性。(2月4日Nature Methods “Taking control with ...

引言在肿瘤的微观宇宙中，每个癌细胞都像是携带双重身份的特工：它的DNA中潜藏着驱动恶性行为的突变密码，而RNA则实时演绎着这些指令带来的致命行动。然而，研究人员长久以来被迫以“分屏视角”观察这场阴谋——单细胞RNA测序（scRNA-seq）揭示细胞的行为特征，单细胞DNA测序（scDNA-seq）捕捉基因组的异常，但二者如同断线 ...

Roche's innovative sequencing by expansion (SBX) technology represents a leap forward in next-generation sequencing (NGS), which is playing a vital role in decoding complex diseases like cancer, ...

Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers.

From understanding hereditary diseases to predicting drug responses, sequencing helps researchers uncover the subtle language ...

Recent research has produced the first high-resolution molecular image of the equine endometrium, the inner lining of the ...

A new study has uncovered key genetic factors that influence both biomass and sugar content in sugar beet, a critical crop ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

The new technology – Cleavage Under Targeted Accessible Chromatin (CUTAC) – focuses on small, fragmented DNA non-coding ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...

A new method, "smol-seq," utilizes DNA sequencing for rapid and precise metabolite detection. It employs DNA aptamers, each with a unique barcode, to bind specific metabolites.