Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer ...

EZH1 is a key regulator of circadian rhythms, stabilizing gene transcription and modifying chromatin to maintain genetic ...

It both stabilizes a critical protein called RNA Polymerase II — the molecular engine of gene transcription — and reshapes the structure of chromatin, the tightly packed form of DNA ...

At the time, researchers were unsure whether histones in the nucleosomes dissociated or remained bound to the DNA as the chromatin uncoiled and RNA polymerase began its job transcribing genes. It was ...

It both stabilizes a critical protein called RNA Polymerase II—the molecular engine of gene transcription—and reshapes the structure of chromatin, the tightly packed form of DNA, to activate ...

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately ...

RNA Synthesis (Transcription) The genetic information stored in DNA is transcribed into RNA through the process of transcription. In this process, the enzyme RNA polymerase uses one strand of the DNA ...

These modifications correlate with metabolic states, impacting chromatin accessibility and transcription ... Ribonucleic acid (RNA)-mediated interference experiments employed short hairpin ...