There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

Because infected host cells ordinarily lack RNA-dependent RNA polymerase (RdRp) activity, these RNA viruses encode a replicative polymerase essential for the production of progeny. Such virally ...

2025年3月12日，中国农业科学院兰州兽医研究所动物病毒分子生态学团队在《美国国家科学院院刊（PNAS）》上发表了题为“ N 6-methyladnosine of vRNA facilitatesinfluenza A virus ...

Eukaryotes transcribe much of their genomes, but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo.I suggest that ∼ 90% of Pol II initiation events in ...

2025年3月12日，中国农业科学院兰州兽医研究所动物病毒分子生态学团队在《美国国家科学院院刊（PNAS）》上发表了题为“N6-methyladnosine of vRNA facilitates influenza A virus ...

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Scientists use RNA origami to fold biomolecules into nanotubes, forming cytoskeleton-like structures, advancing synthetic biology toward artificial cells.

RNA synthesis, or transcription, is the process by which RNA is produced using DNA as a template. This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on ...

Although several vaccines and drugs are available against SARS-CoV-2, the search for effective therapeutic agents for COVID-19 and future zoonotic coronaviruses continues. The RNA-dependent RNA ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...