Surprisingly, the team found that the DHX9 granules, as a special type of stress granule, were packed with damaged RNA. "The damaging effect of UV light on RNA is frequently underestimated ...

These two types of RNA granules aggregate translationally-silenced mRNAs and function as an extension of translation regulation and are key structures that regulate the mRNA cycle. Translational ...

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

New research suggests that the formation of stress granules, clumps of proteins and RNA under stress, is a potential root cause of Alzheimer's disease. These granules affect biological processes, such ...

After UV-induced RNA damage, the proteins DHX9 (green) and G3BP1 (red) form stress granules in the cytoplasm. The cell nuclei are displayed in blue colour. DHX9 is also found in the nucleus.

Hafren, A., Lõhmus, A, and Mäkinen, K. (2015) “Formation of Potato virus A-induced RNA granules and viral translation are interrelated processes required for optimal virus accumulation” PLOS Pathogens ...

Tyler received his Bachelor of Science in Molecular and Cellular Biology from Johns Hopkins University in 2022 where he performed research on RNA-stress granules under Dr. Tatjana Trcek. Before coming ...

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival. Comprised of RNA-binding proteins and ...