RNA abundance is regulated by balancing transcription and degradation in processes that control the temporal and spatial distribution of cellular RNA. In eukaryotic cells, mRNA decay is catalyzed by ...

which makes RNA more unstable and more prone to degradation. RNA is synthesized from DNA by an enzyme known as RNA polymerase during a process called transcription. The new RNA sequences are ...

2025 年 2 月 20 日，中国科学技术大学生命科学与医学部单革教授团队在 Circulation 在线发表题为“ Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure with Exogenous MecciRNA ” 的研究论文 ...

These RNA molecules can interact with mRNA, influencing its stability, translation, or degradation, thus fine-tuning protein production in the cell. RNA interference (RNAi) is a cellular mechanism ...

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than DNA, whether chemical, ...

Ironically, eRNA’s rapid degradation could allow it to provide a more accurate snapshot of what organisms are currently in a system, scientists posit. Moreover, the RNA an organism sheds can change ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to ... They have a shorter lifespan and are prone to degradation by cellular enzymes called ribonucleases (RNases ...

T he RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai ...

They also proved that its genes are directly activated by ManNAc—the initial degradation product of Neu5Ac ... a novel small noncoding RNA of 80 nt in length. Importantly, ManS was produced ...