The study's success demonstrates the potential effectiveness of PASA16 phage therapy in tackling challenging Pseudomonas aeruginosa infections, paving the way for future clinical trials and ...

More information: Ravi K. Lokareddy et al, Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor, Nature Communications (2024). DOI: 10.1038/s41467-024-52752-1.

Electron microscopy (EM) image of Pseudomonas phage Pf, an inovirus infecting Pseudomonas hosts. Inovirus capsids are long flexible filaments visible here after sample concentration and precipitation.

Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. Nature Communications , 2024; 15 (1) DOI: 10.1038/s41467-024-52752-1 Cite This Page : ...

Co-authors with Cingolani and Briani in the DEV study, “Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor,” are Ravi K. Lokareddy, UAB Department of Biochemistry ...

Researchers describe the full molecular structure of the phage DEV. DEV infects and lyses Pseudomonas aeruginosa bacteria, an opportunistic pathogen in cystic fibrosis and other diseases. DEV ...

The Pseudomonas aeruginosa strain in the outbreak is exceedingly rare and had never before been seen in the U.S. It is especially challenging for doctors to treat given it has developed resistance ...

AmpliPhi Biosciences Granted Japanese Patent Covering the Use of Phage Therapy to Resensitize Pseudomonas aeruginosa Infections to Antibiotics August 04, 2016 08:45 AM Eastern Daylight Time ...

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more ...

New structural biology research uncovers how a phage uses a genome ejection motor to infect bacteria, advancing our understanding of phage-bacterial interaction. ... Researchers have described the ...