Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.

Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein kinase that switches off lipid synthesis. The yeast orthologue, the SNF1 complex, was discovered in screens for mutations ...

Researchers have unveiled the first real look at a mitochondrial protein strongly linked to Parkinson's disease, revealing ...

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

For example, 45 human protein kinases lack at least one of the conserved catalytic residues 2 and may not have kinase activity. Kinase activity has not been detected for several CDK-related ...

Researchers have discovered a new approach to prostate cancer treatment by combining immunotherapy with PIM1 kinase ...

Discover a study that used the Skindex-29 assessment to evaluate emotional wellbeing during selumetinib cycles.

A new study by University of Arizona Health Sciences researchers found that an immunotherapy previously shown to be ...

Scientists at Dongguk University and Korean Research Institute of Bioscience and Biotechnology have disclosed benzofuran compounds targeting heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1) ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

The risk of developing Parkinson's disease is twice as high in men as in women, and new research points to a potential reason ...