Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and ...
Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.
Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein kinase that switches off lipid synthesis. The yeast orthologue, the SNF1 complex, was discovered in screens for mutations ...
2 天
ScienceAlert on MSNKey Parkinson's Protein Structure And Malfunction Revealed For First TimeResearchers have unveiled the first real look at a mitochondrial protein strongly linked to Parkinson's disease, revealing ...
This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...
For example, 45 human protein kinases lack at least one of the conserved catalytic residues 2 and may not have kinase activity. Kinase activity has not been detected for several CDK-related ...
Researchers have discovered a new approach to prostate cancer treatment by combining immunotherapy with PIM1 kinase ...
Discover a study that used the Skindex-29 assessment to evaluate emotional wellbeing during selumetinib cycles.
Scientists at Dongguk University and Korean Research Institute of Bioscience and Biotechnology have disclosed benzofuran compounds targeting heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2B1) ...
Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.
7 天
ScienceAlert on MSNMen Have Higher Risk of Parkinson's, And We May Finally Know WhyThe risk of developing Parkinson's disease is twice as high in men as in women, and new research points to a potential reason ...
4 天
AZoRobotics on MSNUtilizing Machine Learning to Enhance Prediction Accuracy of Kinase InteractionsDeveloped by SHRO and the University of Pisa, KinasePred uses AI to predict kinase interactions, advancing research in ...
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