Creutzfeldt-Jakob disease is an extremely rare and fatal brain-wasting disease that's like a human version of "mad cow." ...

Newly emergent prion diseases such as bovine spongiform encephalopathy, variant Creutzfeldt–Jakob disease (CJD), and chronic wasting disease are a source of critical concern to physicians ...

though it can take years to decades before symptoms like dementia show. But once they do, death soon follows. “The National ...

and Creutzfeldt–Jakob disease (CJD) in humans. In TSEs the normal cellular prion protein (PrP C) is transformed into an infectious disease-associated isoform, PrP Sc — a potential target for ...

There is currently no cure for prion disease, and the new approach could ... its progression in patients who have already developed symptoms. A base-editing approach could also likely be a one ...

There is currently no cure for prion disease, and the new approach could ... its progression in patients who have already developed symptoms. A base-editing approach could also likely be a one ...

this has been termed a 'subversion of function'. If so, PrP C contributes to neurotoxicity in prion disease but by uncertain mechnisms.

Feraud Director of the Center for Alzheimer’s Disease Research, wins the 2025 Rainwater Prize for Innovative Early-Career ...