Alternative polyadenylation (APA) is a crucial mechanism in gene regulation that allows a single gene to produce multiple mRNA isoforms by using different polyadenylation sites. This process ...

This means that alternative polyadenylation is a new and widespread mechanism for cancer cells to overexpress oncogenes. Wanting to start my own lab to answer this and other questions, I decided to ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation ... We are interested ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...