“Phospho-tau in blood is not as specific as everyone would like to think ... Zetterberg noted there are already tests that can distinguish tau produced in the brain from tau produced elsewhere in the ...

The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of the notorious tau protein, which can contribute to Alzheimer ...

The scientists produced these organoids from stem cells derived from healthy people as well as from patients with ...

recognizes the PKA-dependent phosphorylation of ser409 in tau; immunoreactivity with neurofibrillary pathology in both early and advanced Alzheimer’s disease, but not in normal brain tissue; reacts ...

However, the clumping of tau protein into well-ordered structures ... More information: Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

Get Instant Summarized Text (Gist) Glutamate, a neurotransmitter, can lead to a toxic buildup of tau protein, contributing to Alzheimer's and related diseases. Research using lab mice and human ...

Stem cell scientists from the University of Southern California (USC) and elsewhere have found a way to potentially clear out the buildup of tau protein in the brain, which is associated with the ...