Phosphorylation enables tau protein to undergo reversible liquid–liquid phase separation (LLPS), forming micrometer-sized droplets, a property not seen in unmodified tau.

Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from ...

Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

But now, Canadian scientists say children who have Dad's with Alzheimer's are more prone to one toxic protein, tau, spreading in the brain. Significant clumps of this protein, as well as anothe ...

recognizes the PKA-dependent phosphorylation of ser409 in tau; immunoreactivity with neurofibrillary pathology in both early and advanced Alzheimer’s disease, but not in normal brain tissue; reacts ...

The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. "We were surprised to see that people with a father with Alzheimer's ...

Researchers have found that tau protein levels detected on brain scans of living people may serve as a biomarker of chronic traumatic encephalopathy, a brain disease that has been linked to repeated ...