Apoptotic-cell phagocytosis by dendritic cells. CFSE-labeled (Molecular Probes, Eugene, Oregon) cloned T cells were induced into apoptosis by exposure to anti-CD95 for 4 h. Apoptotic cells were ...

Phagocytosis of apoptotic cells protects the immediate neighbourhood from direct damage by degradative cellular components (for example, proteases 3) leaking from dead cells.

Efferocytosis is performed upon recognition of “eat-me” signals present in the outer membrane of apoptotic cells. Tissue-resident macrophages posses a wide variety of phagocytic receptors that vary ...