Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene ...

Hence, understanding the role of a given molecule or pathway in immune system function ... on a high-throughput scale (serial analysis of gene expression) or have yet to be proven reliable for ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

The process of complex diseases is closely related to the dysregulation of key biological pathways, it is crucial to identify the dysfunctional ...

Variant, a company dedicated to developing innovative treatments for orphan inherited eye diseases, and the Rare Ocular Diseases Center at the University of Campania Luigi Vanvitelli (UCLV) in Naples ...

While a transient over-expression of the gene can permanently turn feet scales into feathers, it is much harder to disrupt ...

The researchers started by analyzing gene expression in shrews across different points in the lifecycle ... of transcripts that code for components of inhibitory synapses and downregulation of several ...

Single-cell RNA sequencing (scRNA-seq) was performed to analyze cell population characteristics and pathological gene expression patterns ... The type I IFN signaling pathway was found to be ...

The following is a summary of “Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization ...