Neuropathic pain is a common problem in clinical practice and one that adversely affects patients' quality of life. Converging evidence from animal and human studies demonstrates that neuropathic ...

Neuropathic pain syndromes remain a major therapeutic challenge, despite considerable research efforts during the past few decades. Many hypotheses about the mechanisms of pain generation have ...

However, its pathogenesis is still poorly understood ... The genetic and protein alterations that underlie the development of neuropathic pain. Following nerve injury, a series of changes occurring in ...

Neuropathic osteoarthropathy ... The initial fibers damaged are the pain and temperature sensory fibers as they cross the midline. Their loss in the upper extremity, with intact position sense ...

A painkiller developed by Germany's Algiax Pharma has shown efficacy in the treatment of chronic neuropathic pain, another positive development in the search for alternatives to opioids.