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生物通
9 天
靶向剪接因子SNRPB通过保留POLD1内含子抑制子宫内膜癌进展
在卵巢癌中,它可通过抑制 POLA1 和 BRCA2 外显子 3 跳跃促进肿瘤生长和转移;在宫颈癌和甲状腺癌中,它可通过抑制 p53 表达促进肿瘤进展 ... 生成的 Sashimi 图可视化映射到 POLD1 的 RNA 测序(RNA-seq)读数。 (二)组织样本 从山东大学齐鲁医院获取子宫内膜癌 ...
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