Distribution of Ranvier nodes along myelinated axons is a critical determinant of conduction velocity, significantly influencing spike arrival timing and hence neural circuit function. The patterns of ...

Oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role in myelin generation, maintenance, and repair after CNS injuries and in demyelinating diseases.

Goldberg, M.P. Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nature Med. 4, 291–297 ( 1998).

Fibrobiologics' cell therapy CYMS101 significantly increased myelin production and promoted myelin repair in a mouse model of ...