Causing mice to express more C1QL1, however, led to increased numbers of oligodendrocytes and more myelination upon drug withdrawal, suggesting that C1QL1 helps to restore the damaged myelin layer.

Myelin basic protein is positively charged and gets in between the bilayers to link up the negatively-charged lipids and glue the myelin sheath together." ...

The myelin sheath of nerve fibers was first discovered and described by Rudolf Virchow in 1854. Myelin is composed of about 40% water and the dry mass is composed of about 80% lipids and 20% protein.

New research published in The FEBS Journal reveals the importance of a protein called C1QL1 for promoting the replacement of the specialized cells that produce myelin.

Myelin promotes the conduction of nerve cell impulses by forming a sheath ... Nina M. et al., Myelin Basic Protein synthesis is regulated by small non-coding RNA 715, EMBO Reports 2012:13, 827 ...

An RNA made by RNLTR12-int helps produce myelin by binding to a transcription factor (called SOX10), which is a protein that regulates the activity of other genes.

The myelin basic protein (MBP) gene is a candidate locus for susceptibility to multiple sclerosis. Several groups have tested a complex (TGGA)n repeat in the 5′ region of this gene for ...

Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.

The findings are not only relevant to basic research, but also to medicine. Targeted stimulation of Nfat proteins could perhaps be used in the future to promote the formation of new myelin sheaths ...

Kedia and colleagues found the Serpina3n oligodendrocytes had swelled with myelin basic protein (MBP), and their processes had fragmented, suggesting they were overwhelmed with myelin. Scanning ...

Pup brains were examined at P7 for myelin basic protein (MBP) in the internal and external capsules using immunohistochemistry. Quantification of MBP mRNA was also undertaken.

Myelin promotes the conduction of nerve cell impulses by forming a sheath around their ... Myelin Basic Protein synthesis is regulated by small non-coding RNA 715. EMBO reports, 2012 ...