Generating a complete multimodal cell census and atlas of the mouse brain through collaborative data collection, tool development and analysis. This atlas combines single-cell transcriptomic ...
The Allen Mouse Brain Common Coordinate Framework (CCFv3), a 3D reference atlas, is based on an average of the inherent fluorescence in the brains of mice imaged using serial two-photon tomography.
In an international collaboration, researchers hope to integrate single-cell and spatial techniques to create a cell atlas of human and primate brains. A cell atlas refers to a comprehensive map and ...
The brain is a complicated network of connections and functions, but its inner machinations remain an enigma. In a huge collaborative effort, researchers profiled millions of cells to chart a cellular ...
As a proof of principle, they generated a 3D interactive atlas of the brain in both normal mice and mouse models of Alzheimer's and Pompe disease, a rare genetic disorder. Sun's lab has made its ...