the clinical application of mouse monoclonal antibodies is limited by the human anti-mouse antibody (HAMA) response. Humanization of mouse monoclonal antibodies or alpaca nanobody by genetic ...

Coupled with next-generation sequencing, this high-dimensional ... (PD1)-targeting antibody the first chicken-derived mouse cross-reactive antibody to enter clinical development; a novel LAG3 ...

2 Since 1986, over 117 monoclonal antibodies have been FDA-approved, beginning with the mouse monoclonal antibody Muromonab-CD3 for kidney transplant rejection. 3 In additional to antibodies from mice ...

Both methods combine antibody-oligonucleotides with existing single-cell RNA-sequencing (scRNA-seq ... and 13 cell-surface proteins of human and mouse immune cells. They showed that CITE-seq ...

A comprehensive proteomic map of liver fibrosis progression and healing in two mouse models identifies etiology-specific extracellular matrix components, laying the foundation for targeted ...