This distinct structure was first observed in 1989 during the analysis of both total and fractionated IgG from camel serum. These antibodies possess a unique antigen-binding site consisting of a ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments for diseases such as cancer, Alzheimer's disease, autoimmune disorders and ...