We even identified the ‘gear lever’, protein subunit NIPBL ... Neurodegenerative diseases “Once we understand how SMC molecular motors shape DNA, we may start asking what goes wrong in ...

How to Shift Gears in a Molecular Motor Jan. 25, 2024 — Scientists have long strived to develop artificial molecular motors that can convert energy into directed motion.

The chain represents DNA which is folded into a loop by the SMC machine. The red and green labelled parts are the NIPBL gear levers that shift the machine’s direction.