However, its regulatory mechanism remains insufficiently understood. Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between mtDNA ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

In addition, the deletion of TEFM resulted in an increase in transcription initiation from the light-strand promoter, as suggested by higher levels of mitochondrial tRNA Pro, but replication ...

Wenwen Li and colleagues started to investigate the role of mitochondrial transcription in cognition in the hippocampus of young and aged mice. Li et al. found a novel coupling mechanism ...