Subjects were randomized to begin estradiol replacement (micronized estradiol [Estrace TM], 2 mg orally each day) or no therapy for 6 weeks in a 12-week, cross-over design with weekly monitoring ...

Several drugs containing bioidentical 17β-estradiol are currently on the market in the form of oral tablets, vaginal cream, rings, nasal spray skin patches and percutaneous gels. Estradiol can be ...