“It’s very interesting to ponder the fact that this could lead to sex differences in the learning, memory, or behavioral abnormalities associated with [Down syndrome].” Although Gardiner recognized ...

These Dp1Tyb mice also needed louder sounds to initiate a response in their brains, suggesting they had hearing loss. Using gene mapping, the team narrowed down that a gene called Dyrk1a, found on ...

A century after Down syndrome was first described ... As shown in Figure 4, regions on the arms of mouse chromosomes 10 (MMU10), 16 (MMU16), and 17 (MMU17) are syntenic with regions on the ...

Down syndrome, or trisomy 21, is caused by the presence of a third copy of the 21st chromosome. Affected individuals have ...

There has been no definite link to external stimuli resulting in increased seizure activity, though the association of the syndrome in these mice with movement to different rooms within the ...

A man with Down's syndrome died after his carer "landed on him" when jumping into a swimming pool, an inquest has heard. Michael Parker, 43, died on 12 June 2023 while on holiday in Spain with ...