Abnormal DNA methylation is strongly associated with cancer. The results suggest that, for cancer treatments to be effective, ...

there are significant differences in overall and specific methylation levels between different tissue types and between normal cells and cancer cells from the same tissue. In an interestingly ...

Scientists discovered a molecular switch that may reverse cancer cells, stopping them from growing abnormally.

The role of this EZH2- mediated methylation is two-fold ... which is known to be highly expressed in cancer cells, and the activity of E2F1 transcription factors. The findings demonstrate how ...

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types." ...

Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their ...

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

If DNA is a cell's hardware ... scientists have developed numerous therapies that block abnormal DNA methylation to help prevent cancer progression and metastasis. Currently, epigenetic therapies ...

Research suggests that alcohol causes cancer through at least five ... important nutrient that helps make blood cells and is also involved in DNA methylation. But drinking too much alcohol can ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...