Activation of PPAR-γ in THP-1 cells by either 15-deoxy-Δ 12,14 prostaglandin J 2 (15d-PGJ 2) or TZD promotes changes in surface marker expression ... regulator of macrophage gene expression.

Specifically, we aim to discover novel genes and their encoded products that could serve as drugs, drug targets or diagnostic markers for ... most notably in macrophage foam cells, that is ...

Inhibiting GLS1 reduced high blood pressure in the right side of the heart of PAH rats and improved various measures of heart ...

Her writing focuses on gene editing technology, cell and gene therapies ... so they remove them based on the Ly6G marker, and they also removed these macrophages from their analysis,” speculated ...

"In the current study, together with colleagues from MedUni Vienna, we used genetic approaches to investigate the function of PHGDH in macrophages," explains study lead author Zhengnan Cai ...