Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could ... who was not involved in the study. But the pathway might function differently in other cells, including ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

Researchers combined animal models, human brain tissue, and molecular analysis to uncover a connection between Alzheimer's ...

The function of lysosomes is tightly regulated by complex cellular signals, including calcium ions moving into and out of lysosomes. Scientists have known how lysosomes release their calcium since ...

Early work revealed that TFEB is highly effective in ameliorating tau/NFT pathology and rescuing cognitive impairment and neurodegeneration. TFEB targets only the aberrant tau species and this ...

The protein Spns1 helps transport fat molecules out of lysosomes, preventing harmful buildup and offering insights for rare ...

New research has made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat ...

Breakthrough NUS discovery sheds light on cellular recycling mechanism and potential for treating rare diseases Singapore ...