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12 天
建立通用四价 HPV 疫苗体外相对效力(IVRP)检测方法取代体内效力试验
在检测分析技术上,运用酶联免疫吸附试验(ELISA)检测抗体结合活性;通过假病毒中和试验(PBNA)测定中和活性;采用抗体竞争试验筛选识别优势表位的抗体;借助冷冻电镜(cryo-EM)解析 HPV L1 与抗体复合物的结构;同时进行体内效力和体外效力试验 ...
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